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The verb 'to disguise' is one of those verbs ending in the sound 'EYES' (IPA: /aɪz/) for which, despite the advice in -ise - -ize, the spelling with -ise "is compulsory" (Burchfield's Fowler, s.v. -ise).

This is largely because 'disguise' is not, unlike most verbs with this ending, derived from an ancient Greek root. It is derived, via French, from an Old Teutonic origin which also gave the Old English wise, meaning 'way' or 'manner': see also gu-.